What are they? Polyhydroxy acids (PHA’s), also known as gluconolactone or lactobionic acid, are one of the newest members of the alpha hydroxy acid family to hit the skincare market. Made up of larger molecules than traditional AHA’s, polyhydroxy acids are generally considered to be gentler on the skin, causing fewer episodes of peeling, flaking or dryness. Also, unlike certain AHA’s which can over-dry the skin, PHA’s are ideal for sensitive or dry skin types.

You’ll find them in: Polyhydroxy acids are frequently used in anti-aging and correcting skin treatments such as face lotions or creams, serums and eye products. Additionally, PHA’s can be found in acne treatments and are also often found in treatment products for the body, hands, feet and even hair.

Our product picks: Look to NeoStrata for a bounty of options. NeoStrata Facial Cleanser - PHA 4, with 4% gluconolactone, is a cleanser suitable for all skin types, even dry. To combat fine lines and wrinkles, apply NeoStrata Bionic Lotion, with 12% gluconolactone to the face daily. Then, maintain and defend this newly refined skin with NeoStrata Daytime Protection Cream - SPF 15, with 8% gluconolactone and broad-spectrum sun protection. Finally, don’t forget the eyes! Pamper those peepers with NeoStrata Bionic Eye Cream, a hydrating eye cream loaded with antioxidants, green tea and cucumber extracts to combat dark circles and puffiness.

What you can expect: Consistent use of products containing polyhydroxy acids should reveal smoother skin, minimize blemishes or imperfections and help refine small lines or wrinkles. Also, continued use may also help to break up hyperpigmentation and dark spots from sun damage.

Who should avoid them? Although generally considered safe for all skin types, anyone with a known allergy or sensitivity to either polyhydroxy acids or alpha hydroxy acids should check with a dermatologist or doctor before starting any skincare regimen that includes PHA’s. Also, anyone undergoing prescription drug treatment for acne (especially the use of topical retinol products or Accutane) should avoid the use of any type of acid product until treatment is complete or until checking with a doctor.

See also:

Alpha Hydroxy Acids

Salicylic Acid

Glycolic Acid